Apoorva Uboveja

Postdoc

Apoorva has always been interested to pursue a research career in cancer biology and her journey started in 2010 from Bhaskaracharya College of Applied Sciences, University of Delhi, India where she completed her Bachelor’s degree in Biomedical Sciences. During this period she had the opportunity to work on chronic myeloid leukemia in which she determined the expression of p53 tumor suppressor gene in CML patient samples. This project ignited a further spark in her to work in the field of cancer biology. Then she completed her Master’s degree in Biotechnology from South Asian University, India. In July 2015, she started her Ph.D at Dr.B.R.Ambedkar Centre for Biomedical Sciences, University of Delhi, India where she obtained Junior and Senior Research Fellowship from Department of Biotechnology, India. Her Ph.D project was based on elucidating the molecular mechanisms by which p73 tumor suppressor gene exerts its anti-metastatic potential in colorectal cancer cells. In this direction, she has identified two major molecular targets through which p73 exerts its tumor suppressor functions- Neuron Navigator-3 and long non-coding RNA FER1L4. 

Apoorva was awarded with an international travel grant in April 2019 from Department of Biotechnology, India to present her findings at Robinson College, University of Cambridge, United Kingdom. She has also been awarded AACR2021 Global Scholar-In-Training award for her Ph.D work. In the Aird lab, Apoorva is working on the role of metabolic control of the epigenome in ovarian cancer and the contribution of this pathway to tumorigenesis and therapeutic response. Read Apoorva’s preprint on alpha-ketoglutarate and histone acetylation here: https://www.biorxiv.org/content/10.1101/2024.02.06.578742v1

Apoorva is funded by an Ovarian Cancer Research Alliance Mentored Investigator Grant and a HERA Ovarian Cancer Foundation Outside-the-Box grant. She is also a Hillman Postdoc for Innovative Research.